HCP-D T1w/T2w Development
A functional latent mixture model was used to identify groups of cortical parcels exhibiting similar age-related patterns of T1w/T2w growth during youth. (The most parsimonious model identified three latent clusters or groups of cortical parcels with graded differences in the rate of age-related changes in T1w/T2w. Functional latent clusters closely aligned with the sensorimotor-association axis of cortical organization. Sensorimotor areas, primarily in cluster 1 (magenta), had the highest rate of cortical T1w/T2w growth. We observed graded decreases in the rate of cortical T1w/T2w growth in cluster 2 (orange), which included heteromodal association parcels in frontoparietal and temporal cortex, and further in cluster 3 (yellow), which included paralimbic association parcels in the medial prefrontal and insular cortices.